Single-subject research is a group of research methods that are used extensively in the experimental analysis of behavior and applied behavior analysis with both human and non-human participants. This research strategy focuses on one participant and tracks their progress in the research topic over a period of time. Single-subject research allows researchers to track changes in an individual over a large stretch of time instead of observing different people at different stages. This type of research can provide critical data in several fields, specifically psychology. It is most commonly used in experimental and applied analysis of behaviors. This research has been heavily debated over the years. Some believe that this research method is not effective at all while others praise the data that can be collected from it. Principal methods in this type of research are: A-B-A-B designs, Multi-element designs, Multiple Baseline designs, Repeated acquisition designs, Brief experimental designs and Combined designs.

These methods form the heart of the data collection and analytic code of behavior analysis. Behavior analysis is data driven, inductive, and disinclined to hypothetico-deductive methods.